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The chondrodystrophy, nanomelia: biosynthesis and processing of the defective aggrecan precursor.
The lethal chicken mutation nanomelia leads to severe skeletal defects because of a deficiency of aggrecan, which is the largest aggregating chondroitin sulphate proteoglycan of cartilage. In previous work, we have demonstrated that nanomelic chondrocytes produce a truncated aggrecan precursor that...
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Auteurs principaux: | , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
1994
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1137164/ https://ncbi.nlm.nih.gov/pubmed/8037674 |
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