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The chondrodystrophy, nanomelia: biosynthesis and processing of the defective aggrecan precursor.

The lethal chicken mutation nanomelia leads to severe skeletal defects because of a deficiency of aggrecan, which is the largest aggregating chondroitin sulphate proteoglycan of cartilage. In previous work, we have demonstrated that nanomelic chondrocytes produce a truncated aggrecan precursor that...

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Détails bibliographiques
Auteurs principaux: Vertel, B M, Grier, B L, Li, H, Schwartz, N B
Format: Artigo
Langue:Inglês
Publié: 1994
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1137164/
https://ncbi.nlm.nih.gov/pubmed/8037674
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