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Glutathione analogues as novel inhibitors of rat and human glutathione S-transferase isoenzymes, as well as of glutathione conjugation in isolated rat hepatocytes and in the rat in vivo.

Inhibitors of rat and human Alpha- and Mu-class glutathione S-transferases that effectively inhibit the glutathione (GSH) conjugation of bromosulphophthalein in the rat liver cytosolic fraction, isolated rat hepatocytes and in the rat liver in vivo have been developed. The GSH analogue (R)-5-carboxy...

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Autors principals: Ouwerkerk-Mahadevan, S, van Boom, J H, Dreef-Tromp, M C, Ploemen, J H, Meyer, D J, Mulder, G J
Format: Artigo
Idioma:Inglês
Publicat: 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1136874/
https://ncbi.nlm.nih.gov/pubmed/7755575
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