C-terminally truncated human O6-alkylguanine-DNA alkyltransferase retains activity.

A cDNA encoding the human O6-alkylguanine-DNA alkyltransferase (ATase; EC 2.1.1.63; methylated-DNA: protein-cysteine methyltransferase) has been manipulated to generate a C-terminally deleted protein which retains full methyl-transfer activity. The elimination of 22 amino-acid residues from the C-te...

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Bibliographic Details
Main Authors: Elder, R H, Tumelty, J, Douglas, K T, Margison, G P, Rafferty, J A
Format: Artigo
Language:Inglês
Published: 1992
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1132851/
https://ncbi.nlm.nih.gov/pubmed/1497608
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