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Inhibitory effect of zinc on stimulated erythropoietin synthesis in HepG2 cells.

The effect of zinc on erythropoietin (EPO) synthesis in HepG2 cells was investigated. The increase in EPO synthesis induced by Co2+ (50 microM), Ni2+ (300 microM) or oxygen (1% O2) was inhibited by the presence of ZnCl2 (50-150 microM) in the tissue-culture medium, whereas basal EPO synthesis was un...

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Sonraí Bibleagrafaíochta
Main Authors: Dittmer, J, Bauer, C
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1992
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1132752/
https://ncbi.nlm.nih.gov/pubmed/1322122
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