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Human myocardial cytosolic Ca(2+)-independent phospholipase A2 is modulated by ATP. Concordant ATP-induced alterations in enzyme kinetics and mechanism-based inhibition.

Although phospholipases A2 (PLsA2) have been implicated as enzymic mediators of electrophysiological dysfunction during myocardial ischaemia and reperfusion in man, no information on the regulation of human myocardial PLsA2 is available. We now report that human myocardial cytosolic Ca(2+)-independe...

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Bibliografiske detaljer
Main Authors: Hazen, S L, Gross, R W
Format: Artigo
Sprog:Inglês
Udgivet: 1991
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1130495/
https://ncbi.nlm.nih.gov/pubmed/1764021
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