Variable Sensitivity of CCR5-Tropic Human Immunodeficiency Virus Type 1 Isolates to Inhibition by RANTES Analogs

Aminooxypentane (AOP)-RANTES efficiently and specifically blocks entry of non-syncytium-inducing (NSI), CCR5-tropic (R5) human immunodeficiency virus type 1 (HIV-1) into host cells. Inhibition appears to be mediated by increased intracellular retention of the CCR5 coreceptor- AOP-RANTES complex and/...

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Auteurs principaux: Torre, Vincent S., Marozsan, Andre J., Albright, Jamie L., Collins, Kalonji R., Hartley, Oliver, Offord, Robin E., Quiñones-Mateu, Miguel E., Arts, Eric J.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2000
Sujets:
Virus-Cell Interactions
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC112010/
https://ncbi.nlm.nih.gov/pubmed/10775626
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