Classical Swine Fever Virus Leader Proteinase N(pro) Is Not Required for Viral Replication in Cell Culture

The sequence encoding the viral leader proteinase N(pro) was replaced by the murine ubiquitin gene in a full-length cDNA clone of the classical swine fever virus (CSFV) strain Alfort/187. The recombinant virus vA187-Ubi showed growth characteristics similar to those of the parent vA187-1 virus. At t...

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Bibliographic Details
Main Authors: Tratschin, Jon-Duri, Moser, Christian, Ruggli, Nicolas, Hofmann, Martin A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Animal Viruses
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC110041/
https://ncbi.nlm.nih.gov/pubmed/9696875
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