Synthetic Toll-Like Receptor 4 Agonists Stimulate Innate Resistance to Infectious Challenge

A compound family of synthetic lipid A mimetics (termed the aminoalkyl glucosaminide phosphates [AGPs]) was evaluated in murine infectious disease models of protection against challenge with Listeria monocytogenes and influenza virus. For the Listeria model, intravenous administration of AGPs was fo...

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Autores principales: Cluff, Christopher W., Baldridge, Jory R., Stöver, Axel G., Evans, Jay T., Johnson, David A., Lacy, Michael J., Clawson, Valerie G., Yorgensen, Vonnie M., Johnson, Craig L., Livesay, Mark T., Hershberg, Robert M., Persing, David H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Host Response and Inflammation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087352/
https://ncbi.nlm.nih.gov/pubmed/15845512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.5.3044-3052.2005
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