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Oral Immunization with a Salmonella typhimurium Vaccine Vector Expressing Recombinant Enterotoxigenic Escherichia coli K99 Fimbriae Elicits Elevated Antibody Titers for Protective Immunity

Bovine enterotoxigenic Escherichia coli (ETEC) continues to cause mortality in piglets and newborn calves. In an effort to develop a safe and effective vaccine for the prevention of F5(+) ETEC infections, a balanced lethal asd(+) plasmid carrying the complete K99 operon was constructed and designate...

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Bibliografiske detaljer
Main Authors: Ascón, Miguel A., Hone, David M., Walters, Nancy, Pascual, David W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC108685/
https://ncbi.nlm.nih.gov/pubmed/9784559
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