PINCH1 Plays an Essential Role in Early Murine Embryonic Development but Is Dispensable in Ventricular Cardiomyocytes

PINCH1, an adaptor protein composed of five LIM domains, mediates protein-protein interactions and functions as a component of the integrin-integrin-linked kinase (ILK) complex. The integrin-ILK signaling complex plays a pivotal role in cell motility, proliferation, and survival during embryonic dev...

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Bibliographische Detailangaben
Hauptverfasser: Liang, Xingqun, Zhou, Qiang, Li, Xiaodong, Sun, Yunfu, Lu, Min, Dalton, Nancy, Ross, John, Chen, Ju
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1069610/
https://ncbi.nlm.nih.gov/pubmed/15798193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.8.3056-3062.2005
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