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Application of linkage analysis to genetic counselling in families with hereditary retinoblastoma.

Six families with retinoblastoma in more than one member were investigated with DNA markers linked to the retinoblastoma locus because direct analysis had not disclosed the gene defect. In all of the families we could identify the affected chromosome and predict the genetic risk with a high level of...

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Библиографические подробности
Главные авторы: Greger, V, Kerst, S, Messmer, E, Höpping, W, Passarge, E, Horsthemke, B
Формат: Artigo
Язык:Inglês
Опубликовано: 1988
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1015499/
https://ncbi.nlm.nih.gov/pubmed/3163379
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