A Complex Dance: Measuring the Multidimensional Worlds of Influenza Virus Evolution and Anti-Influenza Immune Responses

The human antibody response to influenza virus infection or vaccination is as complicated as it is essential for protection against flu. The constant antigenic changes of the virus to escape human herd immunity hinder the yearly selection of vaccine strains since it is hard to predict which virus st...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jiong Wang, Alexander Wiltse, Martin S. Zand
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2019-11-01
Schriftenreihe:Pathogens
Schlagworte:
influenza virus
humoral response
hemagglutinin (ha) of influenza virus
broad neutralizing antibody(bnab)
heterosubtypic immunity of influenza
original antigenic sin “oas”
“universal” influenza vaccine
protein microarray assay
mplex-flu assay
multiple dimensional assay (mda)
Online Zugang:https://www.mdpi.com/2076-0817/8/4/238
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