mRNA Subtype of Cancer-Associated Fibroblasts Significantly Affects Key Characteristics of Head and Neck Cancer Cells

Head and neck squamous cell carcinomas (HNSCC) belong among severe and highly complex malignant diseases showing a high level of heterogeneity and consequently also a variance in therapeutic response, regardless of clinical stage. Our study implies that the progression of HNSCC may be supported by c...

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Main Authors: Barbora Peltanová, Hana Holcová Polanská, Martina Raudenská, Jan Balvan, Jiří Navrátil, Tomáš Vičar, Jaromír Gumulec, Barbora Čechová, Martin Kräter, Jochen Guck, David Kalfeřt, Marek Grega, Jan Plzák, Jan Betka, Michal Masařík
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2022-05-01
Series:Cancers
Assuntos:
cancer
HNSCC
cancer-associated fibroblasts
tumour microenvironment
cell stiffness
Acceso en liña:https://www.mdpi.com/2072-6694/14/9/2286
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