Roles of CaMKIIβ in the neurotoxicity induced by ropivacaine hydrochloride in dorsal root ganglion

Neurotoxicity of local anesthetics is often reported in the clinic, more and more people pay attention to them. CaMKIIβ, a subtype of CaMKII, is detected in the central nervous system. Previous study found that CaMKIIβ mRNA are up-regulated in DRG neurons treated with ropivacaine hydrochloride, as w...

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Bibliographic Details
Main Authors: Xianjie Wen, Yiqun Li, Xingqing Liu, Can Sun, Jinbing Lin, Wenli Zhang, Yabin Wu, Xiaoping Wang
Format: Artigo
Language:Inglês
Published: Taylor & Francis Group 2019-12-01
Series:Artificial Cells, Nanomedicine, and Biotechnology
Subjects:
CaMKIIβ
local anesthetics
neurotoxicity
T-type calcium channel
Online Access:https://www.tandfonline.com/doi/10.1080/21691401.2019.1642208
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