Bone marrow mesenchymal stromal cells attenuate silica-induced pulmonary fibrosis potentially by attenuating Wnt/β-catenin signaling in rats

Abstract Background Pulmonary fibrosis induced by silica dust is an irreversible, chronic, and fibroproliferative lung disease with no effective treatment at present. Previous studies have shown that early intervention with bone marrow mesenchymal stem/stromal cells (BMSCs) has positive effect on an...

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Hauptverfasser: Enguo Zhang, Ye Yang, Shangya Chen, Cheng Peng, Martin F. Lavin, Abrey J. Yeo, Chao Li, Xiaoshan Liu, Yingjun Guan, Xinjing Du, Zhongjun Du, Hua Shao
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2018-11-01
Schriftenreihe:Stem Cell Research & Therapy
Schlagworte:
Silicosis
Bone marrow mesenchymal stem/stromal cells (BMSCs)
Animal model
Pulmonary fibrosis
Transplantation
Cell therapy
Online Zugang:http://link.springer.com/article/10.1186/s13287-018-1045-4
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