ADAR Mediated RNA Editing Modulates MicroRNA Targeting in Human Breast Cancer

RNA editing by RNA specific adenosine deaminase acting on RNA (ADAR) is increasingly being found to alter microRNA (miRNA) regulation. Editing of miRNA transcripts can affect their processing, as well as which messenger RNAs (mRNAs) they target. Further, editing of target mRNAs can also affect their...

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Hlavní autoři: Justin T. Roberts, Dillon G. Patterson, Valeria M. King, Shivam V. Amin, Caroline J. Polska, Dominika Houserova, Aline Crucello, Emmaline C. Barnhill, Molly M. Miller, Timothy D. Sherman, Glen M. Borchert
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2018-04-01
Edice:Processes
Témata:
ADAR
breast
cancer
inosine
microRNA
microRNA targeting
RNA editing
On-line přístup:http://www.mdpi.com/2227-9717/6/5/42
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