ADAR Mediated RNA Editing Modulates MicroRNA Targeting in Human Breast Cancer

RNA editing by RNA specific adenosine deaminase acting on RNA (ADAR) is increasingly being found to alter microRNA (miRNA) regulation. Editing of miRNA transcripts can affect their processing, as well as which messenger RNAs (mRNAs) they target. Further, editing of target mRNAs can also affect their...

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Autores principales: Justin T. Roberts, Dillon G. Patterson, Valeria M. King, Shivam V. Amin, Caroline J. Polska, Dominika Houserova, Aline Crucello, Emmaline C. Barnhill, Molly M. Miller, Timothy D. Sherman, Glen M. Borchert
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI AG 2018-04-01
Colección:Processes
Materias:
ADAR
breast
cancer
inosine
microRNA
microRNA targeting
RNA editing
Acceso en línea:http://www.mdpi.com/2227-9717/6/5/42
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