ADAR Mediated RNA Editing Modulates MicroRNA Targeting in Human Breast Cancer

RNA editing by RNA specific adenosine deaminase acting on RNA (ADAR) is increasingly being found to alter microRNA (miRNA) regulation. Editing of miRNA transcripts can affect their processing, as well as which messenger RNAs (mRNAs) they target. Further, editing of target mRNAs can also affect their...

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Autors principals: Justin T. Roberts, Dillon G. Patterson, Valeria M. King, Shivam V. Amin, Caroline J. Polska, Dominika Houserova, Aline Crucello, Emmaline C. Barnhill, Molly M. Miller, Timothy D. Sherman, Glen M. Borchert
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2018-04-01
Col·lecció:Processes
Matèries:
ADAR
breast
cancer
inosine
microRNA
microRNA targeting
RNA editing
Accés en línia:http://www.mdpi.com/2227-9717/6/5/42
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