The Role of scaRNAs in Adjusting Alternative mRNA Splicing in Heart Development

Congenital heart disease (CHD) is a leading cause of death in children <1 year of age. Despite intense effort in the last 10 years, most CHDs (~70%) still have an unknown etiology. Conotruncal based defects, such as Tetralogy of Fallot (TOF), a common complex of devastating heart defects, typ...

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Hlavní autoři: Chloe Nagasawa, Allison Ogren, Nataliya Kibiryeva, Jennifer Marshall, James E. O’Brien, Naoya Kenmochi, Douglas C. Bittel
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2018-05-01
Edice:Journal of Cardiovascular Development and Disease
Témata:
alternative mRNA splicing
congenital heart defects
scaRNAs
small cajal body-associated RNAs
tetralogy of Fallot
On-line přístup:http://www.mdpi.com/2308-3425/5/2/26
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