A case of Severe Low-dose Methotrexate-induced Toxicity

Methotrexate (MTX) is an antimetabolite which competitively inhibits dihydrofolic acid reductase; inhibits purine and thymidylic acid synthesis, which in turn interferes with DNA synthesis, repair, and cellular replication. MTX is a good treatment option for neoplastic, rheumatic and dermatological...

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Main Authors: Filiz Topaloğlu Demir, Yavuz Tezcan, Zafer Türkoğlu, Şerife Başaran
Format: Artigo
Jezik:Inglês
Izdano: Galenos Yayinevi 2016-12-01
Serija:Haseki Tıp Bülteni
Teme:
Methotrexate toxicity
mucositis
ulcer
Online dostop:http://www.hasekidergisi.com/article_13413/A-Case-Of-Severe-Low-dose-Methotrexate-induced-Toxicity
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