Mycobacterial phosphatidylinositol mannoside 6 (PIM6) up-regulates TCR-triggered HIV-1 replication in CD4+ T cells.

Tuberculosis (TB) is the leading cause of mortality among those infected with human immunodeficiency virus (HIV-1) worldwide. HIV-1 load and heterogeneity are increased both locally and systemically in active TB. Mycobacterium tuberculosis (MTB) infection supports HIV-1 replication through dysregula...

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Autores principales: Myriam E Rodriguez, Candace M Loyd, Xuedong Ding, Ahmad F Karim, David J McDonald, David H Canaday, Roxana E Rojas
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2013-01-01
Colección:PLoS ONE
Acceso en línea:http://europepmc.org/articles/PMC3839890?pdf=render
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