Inhibiting the growth of pancreatic adenocarcinoma in vitro and in vivo through targeted treatment with designer gold nanotherapeutics.

Pancreatic cancer is one of the deadliest of all human malignancies with limited options for therapy. Here, we report the development of an optimized targeted drug delivery system to inhibit advanced stage pancreatic tumor growth in an orthotopic mouse model. METHODPRINCIPAL FINDINGS: Targeting spec...

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Główni autorzy: Rachel A Kudgus, Annamaria Szabolcs, Jameel Ahmad Khan, Chad A Walden, Joel M Reid, J David Robertson, Resham Bhattacharya, Priyabrata Mukherjee
Format: Artigo
Język:Inglês
Wydane: Public Library of Science (PLoS) 2013-01-01
Seria:PLoS ONE
Dostęp online:http://europepmc.org/articles/PMC3590245?pdf=render
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