Dissection of the influenza A virus endocytic routes reveals macropinocytosis as an alternative entry pathway.

Influenza A virus (IAV) enters host cells upon binding of its hemagglutinin glycoprotein to sialylated host cell receptors. Whereas dynamin-dependent, clathrin-mediated endocytosis (CME) is generally considered as the IAV infection pathway, some observations suggest the occurrence of an as yet uncha...

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Autores principales: Erik de Vries, Donna M Tscherne, Marleen J Wienholts, Viviana Cobos-Jiménez, Florine Scholte, Adolfo García-Sastre, Peter J M Rottier, Cornelis A M de Haan
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2011-03-01
Colección:PLoS Pathogens
Acceso en línea:http://europepmc.org/articles/PMC3068995?pdf=render
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