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Synthesis and Biological Evaluation of Thalidomide Derivatives as Potential Anti-Psoriasis Agents

Several thalidomide derivatives were synthesized and evaluated for their anti-inflammatory activity. Introduction of the benzyl group to the parent thalidomide is unfavorable in which 2-(1-benzyl-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione (4a) was inactivated. However, the inhibitory activities o...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kai-Wei Tang, Zih-Chan Lin, Yeh-Long Chen, Cherng-Chyi Tzeng, Jia-You Fang, Chih-Hua Tseng
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI AG 2018-10-01
Cyfres:International Journal of Molecular Sciences
Pynciau:
Mynediad Ar-lein:http://www.mdpi.com/1422-0067/19/10/3061
Tagiau: Ychwanegu Tag
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