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Instrumental Role of Helicobacter pylori γ-Glutamyl Transpeptidase in VacA-Dependent Vacuolation in Gastric Epithelial Cells.

Helicobacter pylori causes cellular vacuolation in host cells, a cytotoxic event attributed to vacuolating cytotoxin (VacA) and the presence of permeant weak bases such as ammonia. We report here the role of γ-glutamyl transpeptidase (GGT), a constitutively expressed secretory enzyme of H. pylori, i...

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書誌詳細
主要な著者: Samantha Shi Min Ling, Lawrence Han Boon Khoo, Le-Ann Hwang, Khay Guan Yeoh, Bow Ho
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science (PLoS) 2015-01-01
シリーズ:PLoS ONE
オンライン・アクセス:http://europepmc.org/articles/PMC4482420?pdf=render
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