Innate Immune Function of Mitochondrial Metabolism

Sensing of microbe-associated molecular patterns or danger signals by innate immune receptors drives a complex exchange of information. Innate receptor signaling not only triggers transcriptional events but also induces profound changes in metabolic fluxes, redox balance, and metabolite abundance th...

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Main Authors: David Sancho, Michel Enamorado, Johan Garaude
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017-05-01
Serier:Frontiers in Immunology
Fag:
innate immune response
immunometabolism
electron transport chain
mitochondria
macrophages
dendritic cells
Online adgang:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00527/full
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