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Genome-wide modeling of transcription preinitiation complex disassembly mechanisms using ChIP-chip data.

Apparent occupancy levels of proteins bound to DNA in vivo can now be routinely measured on a genomic scale. A challenge in relating these occupancy levels to assembly mechanisms that are defined with biochemically isolated components lies in the veracity of assumptions made regarding the in vivo sy...

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Autors principals: Eric Samorodnitsky, B Franklin Pugh
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2010-04-01
Col·lecció:PLoS Computational Biology
Accés en línia:http://europepmc.org/articles/PMC2848545?pdf=render
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