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Calreticulin in Essential Thrombocythemia: StressINg OUT the Megakaryocyte Nucleus

Calreticulin (CALR) is a multifaceted protein primarily involved in intracellular protein control processes. The identification of CALR mutations in essential thrombocythemia (ET) and primary myelofibrosis that are mutually exclusive with the JAK2 V617F mutation has stirred an intensive research int...

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Main Authors: Francisco Jose Iborra, Petros Papadopoulos
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2017-05-01
叢編:Frontiers in Oncology
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在線閱讀:http://journal.frontiersin.org/article/10.3389/fonc.2017.00103/full
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