Microsatellite instability (MSI, EMAST) in the pathogenesis of follicular lymphoma

Background. Genetic instability, an important phenomenon involved in oncogenic transformation and tumor progression, is associated with the insufficiency of the multicomponent DNA repair complex, in particular, the nucleotide mismatch repair (MMR) system. The MMR defect manifests itself as abnormali...

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Bibliographic Details
Main Authors: K. A. Sychevskaya, S. K. Kravchenko, N. V. Risinskaya, А. Е. Misyurina, E. E. Nikulina, F. E. Babaeva, A. B. Sudarikov
Format: Artigo
Language:Russo
Published: ABV-press 2021-06-01
Series:Onkogematologiâ
Subjects:
follicular lymphoma
genetic instability
short tandem repeat
microsatellite instability
elevated microsatellite alterations at selected tetranucleotide repeats
loss of heterozygosity
Online Access:https://oncohematology.abvpress.ru/ongm/article/view/475
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