Microsatellite instability (MSI, EMAST) in the pathogenesis of follicular lymphoma

Background. Genetic instability, an important phenomenon involved in oncogenic transformation and tumor progression, is associated with the insufficiency of the multicomponent DNA repair complex, in particular, the nucleotide mismatch repair (MMR) system. The MMR defect manifests itself as abnormali...

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Hlavní autoři: K. A. Sychevskaya, S. K. Kravchenko, N. V. Risinskaya, А. Е. Misyurina, E. E. Nikulina, F. E. Babaeva, A. B. Sudarikov
Médium: Artigo
Jazyk:Russo
Vydáno: ABV-press 2021-06-01
Edice:Onkogematologiâ
Témata:
follicular lymphoma
genetic instability
short tandem repeat
microsatellite instability
elevated microsatellite alterations at selected tetranucleotide repeats
loss of heterozygosity
On-line přístup:https://oncohematology.abvpress.ru/ongm/article/view/475
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