Microsatellite instability (MSI, EMAST) in the pathogenesis of follicular lymphoma

Background. Genetic instability, an important phenomenon involved in oncogenic transformation and tumor progression, is associated with the insufficiency of the multicomponent DNA repair complex, in particular, the nucleotide mismatch repair (MMR) system. The MMR defect manifests itself as abnormali...

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Main Authors: K. A. Sychevskaya, S. K. Kravchenko, N. V. Risinskaya, А. Е. Misyurina, E. E. Nikulina, F. E. Babaeva, A. B. Sudarikov
格式: Artigo
語言:Russo
出版: ABV-press 2021-06-01
叢編:Onkogematologiâ
主題:
follicular lymphoma
genetic instability
short tandem repeat
microsatellite instability
elevated microsatellite alterations at selected tetranucleotide repeats
loss of heterozygosity
在線閱讀:https://oncohematology.abvpress.ru/ongm/article/view/475
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