RASSF1A Promoter Methylation and Kras2 Mutations in Non Small Cell Lung Cancer

In the present studies, we investigated the correlation between RASSF1A promoter methylation status and Kras2 mutations in 65 primary non small cell lung cancer (NSCLC) including 33 adenocarcinomas, 12 large cell carcinomas, and 20 squamous cell carcinomas. Mutational analysis of Kras2 showed: 30% (...

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Autori principali: Jie Li, Zhongqiu Zhang, Zunyan Dai, Anthony P. Popkie, Christoph Plass, Carl Morrison, Yian Wang, Ming You
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2003-07-01
Serie:Neoplasia: An International Journal for Oncology Research
Soggetti:
Kras2
RASSF1A
mutations
methylation
lung cancer
Accesso online:http://www.sciencedirect.com/science/article/pii/S1476558603800295
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