Transcriptome Reveals Granulosa Cells Coping through Redox, Inflammatory and Metabolic Mechanisms under Acute Heat Stress

Heat stress affects granulosa cells (GCs) and the ovarian follicular microenvironment, causing poor oocyte developmental competence and fertility. This study aimed to investigate the physical responses and global transcriptomic changes in bovine GCs to acute heat stress (43 °C for 2 h) in vitro. Hea...

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Main Authors: Abdul Sammad, Hanpeng Luo, Lirong Hu, Huabin Zhu, Yachun Wang
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2022-04-01
Series:Cells
Assuntos:
granulosa cells
heat stress
apoptosis
oxidative stress
steroidogenesis
NF-κB pathway
Acceso en liña:https://www.mdpi.com/2073-4409/11/9/1443
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