The Lysine Specific Demethylase-1 Negatively Regulates the <i>COL9A1</i> Gene in Human Articular Chondrocytes

Osteoarthritis (OA) is a degenerative disease of the joints which is associated with an impaired production of the cartilage matrix by the chondrocytes. Here, we investigated the role of Lysine-Specific Demethylase-1 (LSD1), a chromatin remodeling enzyme whose role in articular chondrocytes was prev...

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Main Authors: Anne-Laure Durand, Alexandre Dufour, Elisabeth Aubert-Foucher, Christine Oger-Desfeux, Marielle Pasdeloup, Sebastien Lustig, Elvire Servien, Gualter Vaz, Emeline Perrier-Groult, Frederic Mallein-Gerin, Jerome E. Lafont
格式: Artigo
語言:Inglês
出版: MDPI AG 2020-08-01
叢編:International Journal of Molecular Sciences
主題:
articular chondrocytes
type IX collagen
lysine demethylase
osteoarthritis
在線閱讀:https://www.mdpi.com/1422-0067/21/17/6322
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