Red Blood Cell BCL-x<sub>L</sub> Is Required for <i>Plasmodium falciparum</i> Survival: Insights into Host-Directed Malaria Therapies

The development of antimalarial drug resistance is an ongoing problem threatening progress towards the elimination of malaria, and antimalarial treatments are urgently needed for drug-resistant malaria infections. Host-directed therapies (HDT) represent an attractive strategy for the development of...

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Autori principali: Coralie Boulet, Ghizal Siddiqui, Taylah L. Gaynor, Christian Doerig, Darren J. Creek, Teresa G. Carvalho
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2022-04-01
Serie:Microorganisms
Soggetti:
BCL-x<sub>L</sub>
malaria
<i>Plasmodium falciparum</i>
host-directed therapy
red blood cells
host–parasite interaction
Accesso online:https://www.mdpi.com/2076-2607/10/4/824
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