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CD200 receptor restriction of myeloid cell responses antagonizes antiviral immunity and facilitates cytomegalovirus persistence within mucosal tissue.
CD200 receptor (CD200R) negatively regulates peripheral and mucosal innate immune responses. Viruses, including herpesviruses, have acquired functional CD200 orthologs, implying that viral exploitation of this pathway is evolutionary advantageous. However, the role that CD200R signaling plays during...
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主要な著者: | , , , , , , , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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Public Library of Science (PLoS)
2015-02-01
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シリーズ: | PLoS Pathogens |
オンライン・アクセス: | https://doi.org/10.1371/journal.ppat.1004641 |
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