Increase of Calcium Sensing Receptor Expression Is Related to Compensatory Insulin Secretion during Aging in Mice.

Type 2 diabetes is caused by both insulin resistance and relative insulin deficiency. To investigate age-related changes in glucose metabolism and development of type 2 diabetes, we compared glucose homeostasis in different groups of C57BL/6J mice ranging in age from 4 months to 20 months (4, 8, 12,...

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Main Authors: Yoon Sin Oh, Eun-Hui Seo, Young-Sun Lee, Sung Chun Cho, Hye Seung Jung, Sang Chul Park, Hee-Sook Jun
Format: Artigo
Language:Inglês
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4956240?pdf=render
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