Loss of TRPV2 Homeostatic Control of Cell Proliferation Drives Tumor Progression

Herein we evaluate the involvement of the TRPV2 channel, belonging to the Transient Receptor Potential Vanilloid channel family (TRPVs), in development and progression of different tumor types. In normal cells, the activation of TRPV2 channels by growth factors, hormones, and endocannabinoids induce...

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Bibliographic Details
Main Authors: Sonia Liberati, Maria Beatrice Morelli, Consuelo Amantini, Valerio Farfariello, Matteo Santoni, Alessandro Conti, Massimo Nabissi, Stefano Cascinu, Giorgio Santoni
Format: Artigo
Language:Inglês
Published: MDPI AG 2014-02-01
Series:Cells
Subjects:
Transient Receptor Potential Channels
Transient Receptor Potential Vanilloid-type 2
tumor progression
glioblastoma
prostate cancer
transitional cell carcinoma of human bladder
hepatocarcinoma
Online Access:http://www.mdpi.com/2073-4409/3/1/112
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