Active compound chrysophanol of Cassia tora seeds suppresses heat-induced lipogenesis via inactivation of JNK/p38 MAPK signaling in human sebocytes

Abstract Background Heat induced by infrared (IR) radiation from sun exposure increases skin temperature and can lead to thermal and photo-aging. However, little is known about the relationship between heat induced by IR radiation and lipid biosynthesis in human sebocytes. This study investigated th...

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Hauptverfasser: Hyuk Chul Kwon, Tae Yang Kim, Chun Mong Lee, Kwang Sik Lee, Kun Kook Lee
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2019-06-01
Schriftenreihe:Lipids in Health and Disease
Schlagworte:
Human sebocytes
Acne vulgaris
Cassia tora seed extract
Chrysophanol
MAPK pathways
Heat-shock
Online Zugang:http://link.springer.com/article/10.1186/s12944-019-1072-x
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