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Aggregation chimeras provide evidence of in vivo intercellular correction in ovine CLN6 neuronal ceroid lipofuscinosis (Batten disease)
The neuronal ceroid lipofuscinoses (NCLs; Batten disease) are fatal, mainly childhood, inherited neurodegenerative lysosomal storage diseases. Sheep affected with a CLN6 form display progressive regionally defined glial activation and subsequent neurodegeneration, indicating that neuroinflammation m...
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Hauptverfasser: | , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
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Public Library of Science (PLoS)
2022-01-01
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Schriftenreihe: | PLoS ONE |
Online Zugang: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000108/?tool=EBI |
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