The use of sensitive chemical antibodies for diagnosis: detection of low levels of EpCAM in breast cancer.

EpCAM is expressed at low levels in a variety of normal human epithelial tissues, but is overexpressed in 70-90% of carcinomas. From a clinico-pathological point of view, this has both prognostic and therapeutic significance. EpCAM was first suggested as a therapeutic target for the treatment of epi...

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Главные авторы: Sarah Shigdar, Christine Qian, Li Lv, Chunwen Pu, Yong Li, Lianhong Li, Manju Marappan, Jia Lin, Lifen Wang, Wei Duan
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science (PLoS) 2013-01-01
Серии:PLoS ONE
Online-ссылка:http://europepmc.org/articles/PMC3584034?pdf=render
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