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Structural and Functional Determinants of Rodent and Human Surfactant Protein A: A Synthesis of Binding and Computational Data
Surfactant protein A (SP-A) provides surfactant stability, first line host defense, and lung homeostasis by binding surfactant phospholipids, pathogens, alveolar macrophages (AMs), and epithelial cells. Non-primates express one SP-A protein whereas humans express two: SP-A1 and SP-A2 with core intra...
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Autors principals: | , , , , , , , |
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
Frontiers Media S.A.
2019-11-01
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Col·lecció: | Frontiers in Immunology |
Matèries: | |
Accés en línia: | https://www.frontiersin.org/article/10.3389/fimmu.2019.02613/full |
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