Atorvastatin activates autophagy and promotes neurological function recovery after spinal cord injury

Atorvastatin, a lipid-lowering medication, provides neuroprotective effects, although the precise mechanisms of action remain unclear. Our previous studies confirmed activated autophagy following spinal cord injury, which was conducive to recovery of neurological functions. We hypothesized that ator...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Shuang Gao, Zhong-ming Zhang, Zhao-liang Shen, Kai Gao, Liang Chang, Yue Guo, Zhuo Li, Wei Wang, Ai-mei Wang
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Wolters Kluwer Medknow Publications 2016-01-01
श्रृंखला:Neural Regeneration Research
विषय:
nerve regeneration; spinal cord injury; secondary injury; statins; atorvastatin; autophagy; Beclin-1; light chain 3B; neuroprotection; apoptosis; motor function recovery; neural regeneration
ऑनलाइन पहुंच:http://www.nrronline.org/article.asp?issn=1673-5374;year=2016;volume=11;issue=6;spage=977;epage=982;aulast=Gao
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