Atorvastatin activates autophagy and promotes neurological function recovery after spinal cord injury

Atorvastatin, a lipid-lowering medication, provides neuroprotective effects, although the precise mechanisms of action remain unclear. Our previous studies confirmed activated autophagy following spinal cord injury, which was conducive to recovery of neurological functions. We hypothesized that ator...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Shuang Gao, Zhong-ming Zhang, Zhao-liang Shen, Kai Gao, Liang Chang, Yue Guo, Zhuo Li, Wei Wang, Ai-mei Wang
التنسيق: Artigo
اللغة:Inglês
منشور في: Wolters Kluwer Medknow Publications 2016-01-01
سلاسل:Neural Regeneration Research
الموضوعات:
nerve regeneration; spinal cord injury; secondary injury; statins; atorvastatin; autophagy; Beclin-1; light chain 3B; neuroprotection; apoptosis; motor function recovery; neural regeneration
الوصول للمادة أونلاين:http://www.nrronline.org/article.asp?issn=1673-5374;year=2016;volume=11;issue=6;spage=977;epage=982;aulast=Gao
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