A critical evaluation of the effect of population size and phenotypic measurement on QTL detection and localization using a large F2 murine mapping population

Population size and phenotypic measurement are two key factors determining the detection power of quantitative trait loci (QTL) mapping. We evaluated how these two controllable factors quantitatively affect the detection of QTL and their localization using a large F2 murine mapping population and fo...

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Bibliographic Details
Main Authors: Xinmin Li, Richard J Quigg, Jian Zhou, Shizhong Xu, Godfred Masinde, Subburaman Mohan, David J. Baylink
Format: Artigo
Language:Inglês
Published: Sociedade Brasileira de Genética 2006-01-01
Series:Genetics and Molecular Biology
Subjects:
QTL mapping
mice
detection power
population size
phenotypic measurement
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572006000100030
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