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SPOC1-mediated antiviral host cell response is antagonized early in human adenovirus type 5 infection.

Little is known about immediate phases after viral infection and how an incoming viral genome complex counteracts host cell defenses, before the start of viral gene expression. Adenovirus (Ad) serves as an ideal model, since entry and onset of gene expression are rapid and highly efficient, and mech...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sabrina Schreiner, Sarah Kinkley, Carolin Bürck, Andreas Mund, Peter Wimmer, Tobias Schubert, Peter Groitl, Hans Will, Thomas Dobner
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2013-01-01
Schriftenreihe:PLoS Pathogens
Online Zugang:http://europepmc.org/articles/PMC3836738?pdf=render
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