Wogonin inhibits in vitro herpes simplex virus type 1 and 2 infection by modulating cellular NF-κB and MAPK pathways

Abstract Background Wogonin, a natural flavonoid-like chemical compound, exhibits anti-inflammatory, antitumor, antiviral, neuroprotective, and anxiolytic effects by modulating a variety of cellular signaling pathways including PI3K-Akt, p53, nuclear factor κB (NF-κB), mitogen-activated protein kina...

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Main Authors: Ying Chu, Xiaowen Lv, Longfeng Zhang, Xingli Fu, Siwei Song, Airong Su, Deyan Chen, Lianhong Xu, Yongfang Wang, Zhiwei Wu, Zhihua Yun
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2020-07-01
Series:BMC Microbiology
Assuntos:
Wogonin
Herpes simplex virus (HSV)
Antiviral activity
Nuclear factor κB (NF-κB)
Mitogen-activated protein kinase (MAPK)
Acceso en liña:http://link.springer.com/article/10.1186/s12866-020-01916-2
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