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Metformin modulates microbiota-derived inosine and ameliorates methamphetamine-induced anxiety and depression-like withdrawal symptoms in mice
Background: Metformin exhibits therapeutic potential in behavioural deficits induced by methamphetamine (METH) in rats. Emerging studies suggest gut microbiota may impact psychiatric symptoms, but there is no direct evidence supporting metformin’s participation in the pathophysiology of withdrawal s...
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| 主要な著者: | , , , , , , , , , , , , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier
2022-05-01
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| シリーズ: | Biomedicine & Pharmacotherapy |
| 主題: | |
| オンライン･アクセス: | http://www.sciencedirect.com/science/article/pii/S0753332222002256 |
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