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GLADIATOR: a global approach for elucidating disease modules

Abstract Background Understanding the genetic basis of disease is an important challenge in biology and medicine. The observation that disease-related proteins often interact with one another has motivated numerous network-based approaches for deciphering disease mechanisms. In particular, protein-p...

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Main Authors: Yael Silberberg, Martin Kupiec, Roded Sharan
Format: Artigo
Jezik:Inglês
Izdano: BMC 2017-05-01
Serija:Genome Medicine
Teme:
Disease gene prediction
Disease modules
Disease pathways
Graphs and networks
Protein-protein interaction network
Hyperinsulinism
Online dostop:http://link.springer.com/article/10.1186/s13073-017-0435-z
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