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Seatbelts in CAR therapy: How Safe Are CARS?
T-cells genetically redirected with a chimeric antigen receptor (CAR) to recognize tumor antigens and kill tumor cells have been infused in several phase 1 clinical trials with success. Due to safety concerns related to on-target/off-tumor effects or cytokine release syndrome, however, strategies to...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
MDPI AG
2015-05-01
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| 叢編: | Pharmaceuticals |
| 主題: | |
| 在線閱讀: | http://www.mdpi.com/1424-8247/8/2/230 |
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